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(11)

EP 3 558 392 A1

(12)

(43) Date of publication: 30.10.2019 Bulletin 2019/44 (21) Application number: 17816711.0 (22) Date of filing: 12.12.2017

(51) International Patent Classification (IPC):  A61K 47/69(2017.01) A61P 35/00(2006.01) B82Y 5/00(2011.01) A61K 49/00(2006.01) A61K 49/04(2006.01) (86) International application number: PCT/EP2017/082324 (87) International publication number: WO 2018/114447 (28.06.2018 Gazette 2018/26)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD TN (30) Priority: 21.12.2016 EP 16205708 (71) Applicant: Université de Namur 5000 Namur (BE)	(72) Inventors: BONIFAZI, Davide CF23 5AJ Cardiff Wales (GB) CORVAGLIA, Valentina 00013 Mentana (Roma) (IT) MAREGA, Riccardo 5000 Namur (BE) LUCAS, Stéphane 5380 Forville (BE) (74) Representative: Pronovem  Office Van Malderen Avenue Josse Goffin 158 1082 Bruxelles 1082 Bruxelles (BE)