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EP 3 582 775 A1

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(43) Date of publication: 25.12.2019 Bulletin 2019/52 (21) Application number: 18707866.2 (22) Date of filing: 15.02.2018

(51) International Patent Classification (IPC):  A61K 31/444(2006.01) A61K 45/06(2006.01) A61P 35/00(2006.01) A61P 37/06(2006.01) A61P 43/00(2006.01) A61K 31/541(2006.01) A61P 29/00(2006.01) A61P 37/00(2006.01) A61P 37/08(2006.01) (86) International application number: PCT/EP2018/053803 (87) International publication number: WO 2018/149925 (23.08.2018 Gazette 2018/34)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD TN (30) Priority: 17.02.2017 GB 201702603 (71) Applicant: Galapagos NV 2800 Mechelen (BE)	(72) Inventors: BRYS, Reginald, Christophe, Xavier 2800 Mechelen (BE) GALIEN, René, Alexandre 93230 Romainville (FR) DE VOS, Steve, Irma, Joel 2800 Mechelen (BE) AMANTINI, David 93230 Romainville (FR) CLÉMENT-LACROIX, Philippe 93230 Romainville (FR) (74) Representative: Verbeure, Birgit Maria  Galapagos NV Generaal De Wittelaan L11/A3 2800 Mechelen 2800 Mechelen (BE)