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EP 3 582 786 A1

(12)

(43) Date of publication: 25.12.2019 Bulletin 2019/52 (21) Application number: 18736291.8 (22) Date of filing: 08.01.2018

(51) International Patent Classification (IPC):  A61K 31/65(2006.01) A61P 31/04(2006.01) A61K 38/12(2006.01) (86) International application number: PCT/US2018/012809 (87) International publication number: WO 2018/129463 (12.07.2018 Gazette 2018/28)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD TN (30) Priority: 09.01.2017 US 201762444235 P 21.04.2017 US 201762488528 P (71) Applicant: Rempex Pharmaceuticals, Inc. Lincolnshire, Illinois 60069 (US)	(72) Inventors: DUDLEY, Michael N. Lincolnshire, Illinois 60069 (US) GRIFFITH, David C. Lincolnshire, Illinois 60069 (US) (74) Representative: Heller, Benjamin Henry et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)