(19)
(11) EP 3 587 409 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
13.07.2022 Bulletin 2022/28

(45) Mention of the grant of the patent:
01.06.2022 Bulletin 2022/22

(21) Application number: 19187419.7

(22) Date of filing: 29.05.2015
(51) International Patent Classification (IPC): 
C07D 319/12(2006.01)
 A61K 31/7105(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 319/12; A61K 48/0025; A61K 48/005; C12N 15/111; C12N 2310/11; C12N 2310/14; C12N 2310/141; C12N 2320/32; A61K 38/1816; A61K 38/4846; C12Y 304/21022

(54)

BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS

BIOLOGISCH ABBAUBARE LIPIDE ZUR FREISETZUNG VON NUKLEINSÄUREN

LIPIDES BIODÉGRADABLES POUR L'ADMINISTRATION D'ACIDES NUCLÉIQUES

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA

(30) Priority: 30.05.2014 US 201462005266 P

(43) Date of publication of application:
01.01.2020 Bulletin 2020/01

(60) Divisional application:
22175612.5

(62) Application number of the earlier application in accordance with Art. 76 EPC:
15799261.1 / 3148552

(73) Proprietor: Translate Bio, Inc.
Waltham, MA 02451 (US)

(72) Inventors:
  • DEROSA, Frank
    Chelmsford, MA 01824 (US)
  • HEARTLEIN, Michael
    Boxborough, MA 01719 (US)

(74) Representative: Carpmaels & Ransford LLP 
One Southampton Row
London WC1B 5HA
London WC1B 5HA (GB)


(56) References cited: : 
WO-A1-93/18754
US-A1- 2013 209 392
 US-A1- 2013 158 021
US-A1- 2013 331 464
   
  • HAYASHI ET AL.: "Analysis of Amide Bond Formation with an [alpha]-Hydroxy-[beta]-amino Acid Derivative, 3-Amino-2-hydroxy-4-phenylbutanoic Acid, as an Acyl Component: Byproduction of Homobislactone", J. ORG. CHEM., vol. 66, no. 16, 1 August 2001 (2001-08-01), pages 5537-5544, XP055207370, ISSN: 0022-3263, DOI: 10.1021/jo010233o
 
Remarks:
The file contains technical information submitted after the application was filed and not included in this specification
 
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).