(19)

(11)

EP 3 616 205 A1

(12)

(43) Date of publication: 04.03.2020 Bulletin 2020/10 (21) Application number: 18821929.9 (22) Date of filing: 03.12.2018

(51) International Patent Classification (IPC):  G16B 40/20(2019.01) G06N 20/00(2019.01) (86) International application number: PCT/US2018/063658 (87) International publication number: WO 2019/109089 (06.06.2019 Gazette 2019/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.12.2017 US 201762593802 P (71) Applicant: Illumina, Inc. San Diego, CA 92122 (US)	(72) Inventors: ZHANG, Shile San Diego California 92122 (US) WANG, Mengchi La Jolla California 92093 (US) WISE, Aaron San Diego California 92122 (US) KANG, Han San Diego California 92122 (US) ONUCHIC, Vitor Ferreira San Diego California 92122 (US) KRUGLYAK, Kristina San Diego California 92122 (US) (74) Representative: Icosa  83 avenue Denfert-Rochereau 75014 Paris 75014 Paris (FR)