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EP 3 618 707 A1

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(43) Date of publication: 11.03.2020 Bulletin 2020/11 (21) Application number: 18794087.9 (22) Date of filing: 23.04.2018

(51) International Patent Classification (IPC):  A61B 5/0482(2006.01) A61B 5/04(2006.01) A61B 5/0478(2006.01) (86) International application number: PCT/US2018/028962 (87) International publication number: WO 2018/204119 (08.11.2018 Gazette 2018/45)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 03.05.2017 US 201762500500 P (71) Applicant: HRL Laboratories, LLC Malibu, CA 90265 (US)

(72) Inventors: PILLY, Praveen, K. West Hills, CA 91307 (US) HOWARD, Michael, D. Westlake Village, CA 91361 (US) HOFFMANN, Heiko Simi Valley, CA 93065 (US) LU, Tsai-Ching Thousand Oaks, CA 91360 (US) NI, Kang-Yu Calabasas, CA 91301 (US) PAYTON, David, W. Calabasas, CA 91302 (US) (74) Representative: Boult Wade Tennant LLP  Salisbury Square House 8 Salisbury Square London EC4Y 8AP London EC4Y 8AP (GB)