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(11)

EP 3 621 991 A2

(12)

(88) Date of publication A3: 13.12.2018 (43) Date of publication: 18.03.2020 Bulletin 2020/12 (21) Application number: 18732163.3 (22) Date of filing: 09.05.2018

(51) International Patent Classification (IPC):  C07K 16/18(2006.01) C07K 16/36(2006.01) C07K 16/06(2006.01) (86) International application number: PCT/IL2018/050506 (87) International publication number: WO 2018/207184 (15.11.2018 Gazette 2018/46)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 10.05.2017 US 201762503977 P (71) Applicants: Ariel Scientific Innovations Ltd. 4070000 Ariel (IL) Yeda Research and Development Co. Ltd 7610002 Rehovot (IL)	(72) Inventors: PATCHORNIK, Guy 5557215 Kiryat-Ono (IL) NAMBOOTHIRI, Irishi N. N. Powai Mumbai 400076 (IN) SHEVES, Mordechai 7630966 Rehovot (IL) HOWARD, Assaf 4483000 Petach-Tikva (IL) COHEN, Margalit (Maggie) 4924102 Petach-Tikva (IL) (74) Representative: Dennemeyer & Associates S.A.  Postfach 70 04 25 81304 München 81304 München (DE)