ENGINEERING OF A MINIMAL SACAS9 CRISPR/CAS SYSTEM FOR GENE EDITING AND TRANSCRIPTIONAL REGULATION OPTIMIZED BY ENHANCED GUIDE RNA - Patent 3625338

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EP 3 625 338 A1

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(43)	Date of publication:
	25.03.2020 Bulletin 2020/13

(21)	Application number: 17910146.4

(22)	Date of filing: 19.05.2017

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International Patent Classification (IPC):

C12N 9/22^(2006.01)

C12N 15/115^(2010.01)

(86)	International application number:
	PCT/CN2017/085202

(87)	International publication number:
	WO 2018/209712 (22.11.2018 Gazette 2018/47)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME
	Designated Validation States:
	MA MD

(71)	Applicant: Tsinghua University
	Beijing 100084 (CN)

(72)	Inventors:
	XIE, Zhen Beijing 100084 (CN) MA, Dacheng Beijing 100084 (CN) PENG, Shuguang Beijing 100084 (CN)

(74)	Representative: Pföstl, Andreas
	Schwarz & Partner Patentanwälte Wipplingerstraße 30 1010 Wien 1010 Wien (AT)

(54)	ENGINEERING OF A MINIMAL SACAS9 CRISPR/CAS SYSTEM FOR GENE EDITING AND TRANSCRIPTIONAL REGULATION OPTIMIZED BY ENHANCED GUIDE RNA