(19)
(11) EP 3 650 536 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
09.04.2025 Bulletin 2025/15

(45) Mention of the grant of the patent:
04.12.2024 Bulletin 2024/49

(21) Application number: 18827635.6

(22) Date of filing: 05.07.2018
(51) International Patent Classification (IPC): 
C12N 7/00(2006.01)
A61K 39/00(2006.01)
 A61K 39/145(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 39/00; A61K 39/145; C12N 7/00; C12N 2760/16151; C12N 2760/16121
(86) International application number:
PCT/KR2018/007630
(87) International publication number:
WO 2019/009640 (10.01.2019 Gazette 2019/02)

(54)

METHOD FOR PREPARING INFLUENZA WORKING VIRUS SEED STOCK, METHOD FOR PREPARING INFLUENZA VACCINE USING SAME SEED STOCK, AND VIRUS SEED STOCK PREPARED BY SAME METHOD

VERFAHREN ZUR HERSTELLUNG EINER INFLUENZAVIRENSTAMMKULTUR, VERFAHREN ZUR HERSTELLUNG VON INFLUENZA-IMPFSTOFF UNTER VERWENDUNG EINER SOLCHEN STAMMKULTUR UND NACH DIESEM VERFAHREN HERGESTELLTE VIRENSTAMMKULTUR

PROCÉDÉ DE PRÉPARATION DE STOCK DE SEMENCE DE VIRUS OPÉRATIONNEL DE LA GRIPPE, PROCÉDÉ DE PRÉPARATION D'UN VACCIN CONTRE LA GRIPPE À L'AIDE DE CELUI-CI, ET STOCK DE SEMENCE DE VIRUS PRÉPARÉ PAR LE MÊME PROCÉDÉ

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 05.07.2017 KR 20170085472

(43) Date of publication of application:
13.05.2020 Bulletin 2020/20

(73) Proprietor: SK Bioscience Co., Ltd.
Gyeonggi-do 13494 (KR)

(72) Inventors:
  • KIM, Yun Hee
    Seongnam-Si Gyeonggi-do 13515 (KR)
  • PARK, Yong Wook
    Suwon-Si Gyeonggi-do 16494 (KR)
  • HAM, Dong Soo
    Suwon-Si Gyeonggi-do 16493 (KR)
  • JUNG, Hwan Ui
    Seoul 06511 (KR)
  • KIM, Hun
    Suwon-Si Gyeonggi-do 16505 (KR)

(74) Representative: Dehns 
10 Old Bailey
London EC4M 7NG
London EC4M 7NG (GB)


(56) References cited: : 
WO-A1-2009/155168
KR-A- 20090 057 015
KR-A- 20150 056 519
US-A1- 2013 183 741
 WO-A1-2017/072744
KR-A- 20100 045 436
US-A1- 2012 088 228
US-A1- 2016 108 367
   
  • CRISTIAN PAILLET ET AL: "Statistical optimization of influenza H1N1 production from batch cultures of suspension Vero cells (sVero)", VACCINE, vol. 29, no. 41, 12 July 2011 (2011-07-12), pages 7212 - 7217, XP028284689, ISSN: 0264-410X, [retrieved on 20110712], DOI: 10.1016/J.VACCINE.2011.07.016
  • MILIAN, ERNEST ET AL.: "Accelerated Mass Production of Influenza Virus Seed Stocks in HEK-293 Suspension Cell Cultures by Reverse Genetics", VACCINE, vol. 35, no. 26, 8 May 2017 (2017-05-08), pages 3423 - 3430, XP085043854, DOI: doi:10.1016/j.vaccine.2017.04.065
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).