(19)

(11)

EP 3 669 163 A1

(12)

(43) Date of publication: 24.06.2020 Bulletin 2020/26 (21) Application number: 18841411.4 (22) Date of filing: 04.08.2018

(51) International Patent Classification (IPC):  G01N 3/00(2006.01) G01N 33/574(2006.01) G01N 15/10(2006.01) (86) International application number: PCT/US2018/045294 (87) International publication number: WO 2019/028445 (07.02.2019 Gazette 2019/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 04.08.2017 US 201762541552 P (71) Applicant: University of Georgia Research Foundation, Inc. Athens, GA 30602-7411 (US)	(72) Inventor: MAO, Leidong Athens Georgia 30602-7411 (US) (74) Representative: Comoglio, Elena et al Jacobacci & Partners S.p.A. Corso Emilia 8 10152 Torino 10152 Torino (IT)