(19)
(11) EP 3 669 190 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
06.03.2024 Bulletin 2024/10

(45) Mention of the grant of the patent:
01.11.2023 Bulletin 2023/44

(21) Application number: 18765185.6

(22) Date of filing: 07.08.2018
(51) International Patent Classification (IPC): 
G01N 33/50(2006.01)
 C12N 5/071(2010.01)
(52) Cooperative Patent Classification (CPC):
C12N 5/069; G01N 33/5082; C12N 2513/00
(86) International application number:
PCT/IB2018/055944
(87) International publication number:
WO 2019/034966 (21.02.2019 Gazette 2019/08)

(54)

A RELIABLE AND REPRODUCIBLE INDUSTRIALISATION PROCESS FOR THE ELIMINATION OF AIR BUBBLES IN THE PRODUCTION OF AN ENGINEERED VASCULAR TISSUE

ZUVERLÄSSIGES UND REPRODUZIERBARES INDUSTRIALISIERUNGSVERFAHREN ZUR BESEITIGUNG VON LUFTBLASEN BEI DER HERSTELLUNG EINES KÜNSTLICHEN GEFÄSSGEWEBES

PROCÉDÉ D'INDUSTRIALISATION FIABLE ET REPRODUCTIBLE POUR L'ÉLIMINATION DE BULLES D'AIR DANS LA PRODUCTION D'UN TISSU VASCULAIRE RECONSTRUIT

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 16.08.2017 IT 201700093925

(43) Date of publication of application:
24.06.2020 Bulletin 2020/26

(73) Proprietor: 1MED SA
6982 Agno (CH)

(72) Inventors:
  • TRESOLDI, Claudia
    6928 Manno (CH)
  • VANTAGGIATO, Cristina
    6928 Manno (CH)

(74) Representative: Benedetto, Marco 
Marben S.r.l. Via Larga, 16
20122 Milano
20122 Milano (IT)


(56) References cited: : 
WO-A1-2015/134853
 WO-A2-03/082145
   
  • PETER S. MCFETRIDGE ET AL: "Endothelial and Smooth Muscle Cell Seeding onto Processed Ex Vivo Arterial Scaffolds Using 3D Vascular Bioreactors", ASAIO JOURNAL, vol. 50, no. 6, 1 November 2004 (2004-11-01), pages 591-600, XP055181112, ISSN: 1058-2916, DOI: 10.1097/01.MAT.0000144365.22025.9B
  • SEBASTIAN SCHUERLEIN ET AL: "A versatile modular bioreactor platform for Tissue Engineering", BIOTECHNOLOGY JOURNAL, vol. 12, no. 2, 1 February 2017 (2017-02-01), page 1600326, XP055521499, DE ISSN: 1860-6768, DOI: 10.1002/biot.201600326
  • ALIDA ABRUZZO ET AL: "Using Polymeric Scaffolds for Vascular Tissue Engineering", INTERNATIONAL JOURNAL OF POLYMER SCIENCE, vol. 2014, 1 January 2014 (2014-01-01), pages 1-9, XP055470620, ISSN: 1687-9422, DOI: 10.1155/2014/689390
  • ZHANG X ET AL: "Dynamic culture conditions to generate silk-based tissue-engineered vascular grafts", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 30, no. 19, 1 July 2009 (2009-07-01), pages 3213-3223, XP026130537, ISSN: 0142-9612, DOI: 10.1016/J.BIOMATERIALS.2009.02.002 [retrieved on 2009-02-20]
   
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