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EP 3 681 365 A1

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(43) Date of publication: 22.07.2020 Bulletin 2020/30 (21) Application number: 18852871.5 (22) Date of filing: 11.09.2018

(51) International Patent Classification (IPC):  A61B 1/00(2006.01) A61L 27/00(2006.01) C12M 1/12(2006.01) C12M 1/34(2006.01) A61B 5/00(2006.01) C12M 1/00(2006.01) C12M 1/32(2006.01) (86) International application number: PCT/US2018/050467 (87) International publication number: WO 2019/051486 (14.03.2019 Gazette 2019/11)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 11.09.2017 US 201762556646 P 27.02.2018 US 201862636039 P (71) Applicant: 3D Biotek, LLC Bridgewater, NJ 08807 (US)

(72) Inventors: WANG, Zongsen Princeton New Jersey 08540 (US) LAU, Wing Basking Ridge New Jersey 07920 (US) PAYVANDI, Faribourz Belle Mead New Jersey 08502 (US) MATERNA, Peter Metuchen New Jersey 08840 (US) AZADEH, Jadali Coram New York 11727 (US) (74) Representative: Remus, Alvaro Johannes  BPSH Schrooten Haber Remus Patent- und Rechtsanwaltspartnerschaft mbB Grafenberger Allee 277-287, Eingang A 40237 Düsseldorf 40237 Düsseldorf (DE)