(19)

(11)

EP 3 681 861 A1

(12)

(43) Date of publication: 22.07.2020 Bulletin 2020/30 (21) Application number: 18856459.5 (22) Date of filing: 12.09.2018

(51) International Patent Classification (IPC):  C07D 205/00(2006.01) A61K 31/341(2006.01) A61P 29/00(2006.01) A61K 31/167(2006.01) A61K 45/06(2006.01) C07F 9/568(2006.01) (86) International application number: PCT/US2018/050656 (87) International publication number: WO 2019/055509 (21.03.2019 Gazette 2019/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 12.09.2017 US 201715702693 (71) Applicant: Ardea Biosciences, Inc. San Diego, CA 92121 (US)	(72) Inventors: NANAVATI, Payal San Diego, California 92121 (US) HOEGSTEDT, Johan San Diego, California 92121 (US) HALL, Jesse San Diego, California 92121 (US) (74) Representative: HGF  1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB)