(19)
(11) EP 3 691 670 A1

(12)

(43) Date of publication:
12.08.2020 Bulletin 2020/33

(21) Application number: 18864985.9

(22) Date of filing: 02.10.2018
(51) International Patent Classification (IPC): 
A61K 38/00(2006.01)
C07K 7/06(2006.01)
C07K 14/435(2006.01)
 C07K 7/00(2006.01)
C07K 7/08(2006.01)
(86) International application number:
PCT/US2018/053873
(87) International publication number:
WO 2019/070645 (11.04.2019 Gazette 2019/15)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 02.10.2017 US 201762566813 P

(71) Applicant: Cedars-Sinai Medical Center
Los Angeles, CA 90048 (US)

(72) Inventors:
  • HOLLER, Eggehard
    Los Angeles, California 90046 (US)
  • LJUBIMOVA, Julia Y.
    Studio City, California 91604 (US)
  • BLACK, Keith L.
    Los Angeles, California 90077 (US)

(74) Representative: Nederlandsch Octrooibureau 
P.O. Box 29720
2502 LS The Hague
2502 LS The Hague (NL)

   


(54) METHODS AND COMPOSITIONS FOR EFFICIENT DELIVERY THROUGH MULTIPLE BIO BARRIERS