(19)
(11) EP 3 700 925 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
16.02.2022 Bulletin 2022/07

(45) Mention of the grant of the patent:
29.12.2021 Bulletin 2021/52

(21) Application number: 18795783.2

(22) Date of filing: 22.10.2018
(51) International Patent Classification (IPC): 
A61K 38/00(2006.01)
A61K 38/17(2006.01)
 C07K 14/725(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 38/00; C07K 14/7051; A61K 38/17
(86) International application number:
PCT/GB2018/053045
(87) International publication number:
WO 2019/081902 (02.05.2019 Gazette 2019/18)

(54)

NOVEL T-CELL RECEPTOR

NEUARTIGER T-ZELL-REZEPTOR

NOUVEAU RÉCEPTEUR DES LYMPHOCYTES T

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 26.10.2017 GB 201717578
16.04.2018 GB 201806155

(43) Date of publication of application:
02.09.2020 Bulletin 2020/36

(60) Divisional application:
21214567.6

(73) Proprietor: University College Cardiff Consultants Ltd
Cardiff South Glamorgan CF24 0DE (GB)

(72) Inventors:
  • SEWELL, Andrew
    Cardiff South Glamorgan CF14 0XB (GB)
  • DOLTON, Garry
    Cardiff South Glamorgan CF24 3EA (GB)

(74) Representative: Aylett, Sophie-Beth 
Sagittarius IP Marlow International Parkway
Marlow SL7 1YL
Marlow SL7 1YL (GB)


(56) References cited: : 
WO-A1-2018/162563
   
  • EUN JEONG WON ET AL: "Clinical relevance of circulating mucosal-associated invariant T cell levels and their anti-cancer activity in patients with mucosal-associated cancer", ONCOTARGET, vol. 7, no. 46, 15 November 2016 (2016-11-15), XP055469874, United States ISSN: 1949-2553, DOI: 10.18632/oncotarget.11187
  • SIDONIA B.G. ECKLE ET AL: "A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 211, no. 8, 21 July 2014 (2014-07-21) , pages 1585-1600, XP055539284, US ISSN: 0022-1007, DOI: 10.1084/jem.20140484
  • NICK GOLDFINCH ET AL: "Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen", VETERINARY RESEARCH., vol. 41, no. 5, 31 May 2010 (2010-05-31), page 62, XP055539295, NL ISSN: 0928-4249, DOI: 10.1051/vetres/2010034
  • MARIELLE C. GOLD ET AL: "MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 211, no. 8, 21 July 2014 (2014-07-21) , pages 1601-1610, XP055539298, US ISSN: 0022-1007, DOI: 10.1084/jem.20140507
   
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