(19)
(11) EP 3 706 784 A1

(12)

(43) Date of publication:
16.09.2020 Bulletin 2020/38

(21) Application number: 18875943.5

(22) Date of filing: 08.11.2018
(51) International Patent Classification (IPC): 
A61K 39/00(2006.01)
A61K 35/15(2015.01)
(86) International application number:
PCT/US2018/059896
(87) International publication number:
WO 2019/094642 (16.05.2019 Gazette 2019/20)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 08.11.2017 US 201762583229 P
20.11.2017 US 201762588590 P
17.01.2018 US 201862618445 P
27.09.2018 US 201862737625 P

(71) Applicants:
  • BioNTech US Inc.
    Cambridge, MA 02139 (US)
  • Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis
    1066 CX Amsterdam (NL)

(72) Inventors:
  • VAN BUUREN, Marit M.
    Belmont, Massachusetts 02478 (US)
  • LENKALA, Divya Reddy
    Watertown, Massachusetts 02472 (US)
  • VAN DEN BERG, Joost Huibert
    1059 TG Amsterdam (NL)
  • KOHLER, Jessica
    Boston, Massachusetts 02210 (US)
  • GOLDSTEIN, Matthew
    Jamaica Plan, Massachusetts 02130 (US)
  • FRITSCH, Ed
    Concord, Massachusetts 01742 (US)
  • DEBOER, Renate
    1066 CX Amsterdam (NL)
  • SCHUMACHER, Ton
    1066 CX Amsterdam (NL)
  • BAKKER, Noor
    Stuyvesantstraat (NL)

(74) Representative: Avidity IP 
Broers Building Hauser Forum 21 JJ Thomson Avenue
Cambridge CB3 0FA
Cambridge CB3 0FA (GB)

   


(54) T CELL MANUFACTURING COMPOSITIONS AND METHODS