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EP 3 717 470 A1

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(43) Date of publication: 07.10.2020 Bulletin 2020/41 (21) Application number: 18825831.3 (22) Date of filing: 27.11.2018

(51) International Patent Classification (IPC):  C07D 401/14(2006.01) A61P 35/00(2006.01) A61K 38/05(2006.01) A61K 31/444(2006.01) C07K 5/02(2006.01) (86) International application number: PCT/US2018/062598 (87) International publication number: WO 2019/104318 (31.05.2019 Gazette 2019/22)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 27.11.2017 IN 201711042475 07.12.2017 IN 201711044047 05.01.2018 IN 201811000614 08.02.2018 IN 201811004740 27.03.2018 IN 201811011325 24.10.2018 IN 201811040154 (71) Applicant: Assia Chemical Industries Ltd 4951033 Petach Tikva (IL)

(72) Inventors: MUTHUSAMY, Anantha Rajmohan Sivakasi Tamilnadu 626123 (IN) SINGH, Amit Greater Noida Uttar Pradesh 201310 (IN) YAZALI, Venkata Subbarao Guntur Andhra Pradesh 522309 (IN) LUTHRA, Parven Kumar New Delhi New Delhi 110059 (IN) VASOYA, Sanjay Lakhabhai Rajkot Gujarat 360002 (IN) PATIL, Bhatu Tumba Greater Noida Uttar Pradesh 201308 (IN) TANEJA, Amit Kumar Haryana 135001 (IN) SRIVASTAV, Naveen Chandra Greater Noida Uttar Pradesh 201308 (IN) SINGH, Rinku Noida Uttar Pradesh 201304 (IN) RENGASAMY, Vadivelan Tamilnadu 621802 (IN) TYAGI, Abhilash Greater Noida Uttar Pradesh 201308 (IN) (74) Representative: D Young & Co LLP  120 Holborn London EC1N 2DY London EC1N 2DY (GB)