(19)
(11) EP 3 723 863 A1

(12)

(43) Date of publication:
21.10.2020 Bulletin 2020/43

(21) Application number: 18800856.9

(22) Date of filing: 18.10.2018
(51) International Patent Classification (IPC): 
A61P 37/00(2006.01)
A61K 39/00(2006.01)
A61K 9/127(2006.01)
 A61K 39/04(2006.01)
A61K 39/35(2006.01)
(86) International application number:
PCT/EP2018/000479
(87) International publication number:
WO 2019/076478 (25.04.2019 Gazette 2019/17)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 18.10.2017 EP 17001743

(71) Applicants:
  • Luxembourg Institute of Health (LIH)
    4354 Esch-sur-Alzette (LU)
  • Tolerogenics S.à.r.l.
    4354 Esch-sur-Alzette (LU)

(72) Inventors:
  • BREDEHORST, Reinhard
    DE 20255 Hamburg (DE)
  • GRUNWALD, Thomas
    DE 22459 Hamburg (DE)
  • LEONARD, Catherine
    BE 6600 Bastogne (BE)
  • OLLERT, Markus
    2342 Luxembourg (LU)
  • JUNGBLUT, Bernhard
    DE 10589 Berlin (DE)

(74) Representative: Jungblut & Seuss 
Patentanwälte Max-Dohrn-Strasse 10
10589 Berlin
10589 Berlin (DE)

   


(54) HYDROGEL-EMBEDDED OLIGODEOXYNUCLEOTIDES AS TOLEROGENIC ADJUVANT FOR SUBCUTANEOUS IMMUNOTHERAPY