METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE

(19)

(11)

EP 3 734 280 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	24.08.2022 Bulletin 2022/34

(45)	Mention of the grant of the patent:
	01.06.2022 Bulletin 2022/22

(21)	Application number: 20162229.7

(22)	Date of filing: 16.01.2014

(51)

International Patent Classification (IPC):

G01N 33/566^(2006.01)
C40B 30/04^(2006.01)
G01N 33/573^(2006.01)

C12M 1/34^(2006.01)
C40B 60/12^(2006.01)
G01N 33/68^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	G01N 2333/4745; G01N 2333/8146; G01N 2800/347; G01N 2800/50; G16H 50/20; G16B 40/00; G01N 33/6893; Y02A 90/10; G01N 33/68; G16B 40/20

(54)	METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE VERFAHREN UND ZUSAMMENSETZUNGEN ZUR DIAGNOSE UND PROGNOSE VON NIERENLÄSION UND NIERENINSUFFIZIENZ PROCÉDÉS ET COMPOSITIONS POUR LE DIAGNOSTIC ET LE PRONOSTIC DE LÉSIONS RÉNALES ET D'INSUFFISANCE RÉNALE

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30)

Priority:

17.01.2013 US 201361753723 P

(43)	Date of publication of application:
	04.11.2020 Bulletin 2020/45

(60)	Divisional application:
	22176536.5

(62)	Application number of the earlier application in accordance with Art. 76 EPC:
	18157605.9 / 3361255
	14740960.1 / 2946211

(73)	Proprietor: Astute Medical, Inc.
	San Diego, CA 92121 (US)

(72)	Inventors:
	Anderberg, Joseph Encinitas, CA California 92024 (US) Gray, Jeff deceased (US) McPherson, Paul Encinitas, CA California 92024 (US) Nakamura, Kevin Encinitas, CA 92024 (US) Kampf, James Patrick San Diego, CA California 92130 (US)

(74)	Representative: Wilding, James Roger et al
	Mathys & Squire The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)

(56)

References cited: :

WO-A1-2011/035323

US-A1- 2012 283 128

CARON ET AL: "Ischemia injury alters endothelial cell properties of kidney cortex: Stimulation of MMP-9", EXPERIMENTAL CELL RESEARCH, ACADEMIC PRESS, US, vol. 310, no. 1, 15 October 2005 (2005-10-15), pages 105-116, XP005093311, ISSN: 0014-4827, DOI: 10.1016/J.YEXCR.2005.07.004
QIANG YAN ET AL: "Expression of MMP-2 and TIMP-1 in Renal Tissue of Patients with Chronic Active Antibody-mediated Renal Graft Rejection", DIAGNOSTIC PATHOLOGY, BIOMED CENTRAL LTD, LO, vol. 7, no. 1, 12 October 2012 (2012-10-12), page 141, XP021137264, ISSN: 1746-1596, DOI: 10.1186/1746-1596-7-141
MAZANOWSKA O ET AL: "Imbalance of Metallaproteinase/Tissue Inhibitors of Metalloproteinase System in Renal Transplant Recipients With Chronic Allograft Injury", TRANSPLANTATION PROCEEDINGS, vol. 43, no. 8, 2011, pages 3000-3003, XP028311963, ISSN: 0041-1345, DOI: 10.1016/J.TRANSPROCEED.2011.08.012 [retrieved on 2011-08-22]

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).