(19)
(11) EP 3 737 472 A1

(12)

(43) Date of publication:
18.11.2020 Bulletin 2020/47

(21) Application number: 19701776.7

(22) Date of filing: 08.01.2019
(51) International Patent Classification (IPC): 
A61P 25/28(2006.01)
G01N 33/50(2006.01)
A61P 9/00(2006.01)
 C07K 14/435(2006.01)
A61P 21/00(2006.01)
A61P 13/12(2006.01)
(86) International application number:
PCT/EP2019/050354
(87) International publication number:
WO 2019/137922 (18.07.2019 Gazette 2019/29)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 09.01.2018 DE 102018100377

(71) Applicant: Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie
07745 Jena (DE)

(72) Inventors:
  • SKERKA, Christine
    07743 Jena (DE)
  • ZIPFEL, Peter
    07743 Jena (DE)
  • ACKERMANN, Susanne
    99423 Weimar (DE)

(74) Representative: Krauss, Jan 
Boehmert & Boehmert Anwaltspartnerschaft mbB Pettenkoferstrasse 22
80336 München
80336 München (DE)

   


(54) MODULATORS OF C1Q, IN PARTICULAR OF THE INTERACTION OF APOE WITH C1Q, AND USES OF THE MODULATORS IN THE THERAPY OF NEURONAL DISEASES AND INFLAMMATION