(19)

(11)

EP 3 746 050 A1

(12)

(43) Date of publication: 09.12.2020 Bulletin 2020/50 (21) Application number: 19747805.0 (22) Date of filing: 01.02.2019

(51) International Patent Classification (IPC):  A61K 9/08(2006.01) A61K 31/7072(2006.01) A61P 25/00(2006.01) A61K 31/19(2006.01) A61K 45/06(2006.01) (86) International application number: PCT/US2019/016246 (87) International publication number: WO 2019/152776 (08.08.2019 Gazette 2019/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.02.2018 US 201862624911 P 08.08.2018 US 201862715848 P (71) Applicant: Wellstat Therapeutics Corporation Rockville, MD 20850 (US)	(72) Inventors: VON BORSTEL, Reid W. Potomac, MD 20854 (US) GARCIA GARCIA, Rolando, Alejandro Germantown, MD 20874 (US) (74) Representative: MacLean, Martin Robert  Mathys & Squire LLP The Shard 32 London Bridge Street London SE1 9SG The Shard 32 London Bridge Street London SE1 9SG (GB)