(19)

(11)

EP 3 755 312 A1

(12)

(43) Date of publication: 30.12.2020 Bulletin 2020/53 (21) Application number: 19756920.5 (22) Date of filing: 25.02.2019

(51) International Patent Classification (IPC):  A61K 31/137(2006.01) A61P 25/00(2006.01) A61P 25/24(2006.01) A61P 25/30(2006.01) A61K 31/485(2006.01) A61P 25/18(2006.01) A61P 25/28(2006.01) (86) International application number: PCT/US2019/019445 (87) International publication number: WO 2019/165379 (29.08.2019 Gazette 2019/35)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 23.02.2018 US 201862634718 P 18.01.2019 US 201962794469 P 22.02.2019 US 201962809480 P (71) Applicant: Axsome Therapeutics, Inc. New York, NY 10007 (US)	(72) Inventor: TABUTEAU, Herriot New York, NY 10007 (US) (74) Representative: Tana, Maria Gabriella et al Praxi Intellectual Property S.p.A. Via Mario Pagano, 69/A 20145 Milano 20145 Milano (IT)