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EP 3 755 319 A1

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(43) Date of publication: 30.12.2020 Bulletin 2020/53 (21) Application number: 19756654.0 (22) Date of filing: 20.02.2019

(51) International Patent Classification (IPC):  A61K 31/353(2006.01) A61P 19/10(2006.01) C07D 311/74(2006.01) A61P 19/08(2006.01) C07D 311/62(2006.01) (86) International application number: PCT/US2019/018730 (87) International publication number: WO 2019/164914 (29.08.2019 Gazette 2019/35)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 20.02.2018 US 201815900533 (71) Applicant: Epirium Bio Inc. San Diego CA 92122 (US)	(72) Inventors: SCHREINER, George, F. Los Altos Hills, CA 94022 (US) CEBALLOS, Guillermo Atizapan de Zaragoza Edo. de Mexico, 52998 (MX) DUGAR, Sundeep San Jose, CA 95120 (US) (74) Representative: King, Lawrence  A.A. Thornton & Co. 15 Old Bailey London EC4M 7EF London EC4M 7EF (GB)