(19)
(11) EP 3 759 229 A1

(12)

(43) Date of publication:
06.01.2021 Bulletin 2021/01

(21) Application number: 19757688.7

(22) Date of filing: 25.02.2019
(51) International Patent Classification (IPC): 
C12P 21/08(2006.01)
C07K 16/28(2006.01)
A61K 39/395(2006.01)
C12N 5/07(2010.01)
 C07K 14/705(2006.01)
C07K 16/30(2006.01)
A61K 45/06(2006.01)
C12N 5/16(2006.01)
(86) International application number:
PCT/US2019/019340
(87) International publication number:
WO 2019/165340 (29.08.2019 Gazette 2019/35)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 26.02.2018 US 201862635033 P
15.11.2018 US 201862767900 P

(71) Applicant: IGM Biosciences Inc.
Mountain View, CA 94043 (US)

(72) Inventors:
  • WANG, Beatrice Tien-Yi
    Mountain View, California 94040 (US)
  • KEYT, Bruce Alan
    Hillsborough, California 94010 (US)

(74) Representative: Inspicos P/S 
Kogle Allé 2
2970 Hørsholm
2970 Hørsholm (DK)

   


(54) USE OF A MULTIMERIC ANTI-DR5 BINDING MOLECULE IN COMBINATION WITH A CHEMOTHERAPEUTIC AGENT FOR TREATING CANCER