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EP 3 762 086 A1

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(43) Date of publication: 13.01.2021 Bulletin 2021/02 (21) Application number: 19716613.5 (22) Date of filing: 11.03.2019

(51) International Patent Classification (IPC):  A61M 37/00(2006.01) C12N 15/86(2006.01) C12M 1/42(2006.01) (86) International application number: PCT/US2019/021708 (87) International publication number: WO 2019/173850 (12.09.2019 Gazette 2019/37)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 09.03.2018 US 201862641234 P 06.04.2018 US 201815947746 (71) Applicant: Flodesign Sonics Inc. Wilbraham, MA 01095 (US)

(72) Inventors: LIPKENS, Bart Wilbraham, Massachusetts 01095 (US) GHOSHAL, Goutam Wilbraham, Massachusetts 01095 (US) MANZI, Nicholas Wilbraham, Massachusetts 01095 (US) KENNEDY, Thomas J., III Wilbraham, Massachusetts 01095 (US) TOSTOES, Rui Wilbraham, Massachusetts 01095 (US) ROSS-JOHNSRUD, Benjamin Wilbraham, Massachusetts 01095 (US) (74) Representative: Freischem & Partner Patentanwälte mbB  Salierring 47-53 50677 Köln 50677 Köln (DE)