(19)

(11)

EP 3 768 780 A1

(12)

(43) Date of publication: 27.01.2021 Bulletin 2021/04 (21) Application number: 18727416.2 (22) Date of filing: 21.03.2018

(51) International Patent Classification (IPC):  C09B 23/01(2006.01) G01N 33/58(2006.01) A61K 49/00(2006.01) (86) International application number: PCT/IB2018/000390 (87) International publication number: WO 2019/180475 (26.09.2019 Gazette 2019/39)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) 1015 Lausanne (CH)	(72) Inventors: SINISI, Riccardo 1004 Lausanne (CH) MORALES MORALES, Alma Rosa 1015 Lausanne (CH) GOUN, Elena, A. 1015 Lausanne (CH) SINGH, Rajendra 1015 Lausanne (CH) (74) Representative: Gibson, Mark  Sagittarius IP Marlow International Parkway Marlow SL7 1YL Marlow SL7 1YL (GB)