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EP 3 773 685 A1

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(43) Date of publication: 17.02.2021 Bulletin 2021/07 (21) Application number: 19716314.0 (22) Date of filing: 25.03.2019

(51) International Patent Classification (IPC):  A61K 38/46(2006.01) C12N 15/113(2010.01) A61P 31/04(2006.01) C12N 9/22(2006.01) A61P 31/00(2006.01) (86) International application number: PCT/EP2019/057453 (87) International publication number: WO 2019/185551 (03.10.2019 Gazette 2019/40)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 25.03.2018 GB 201804781 28.04.2018 GB 201806976 30.04.2018 US 201815967484 (71) Applicant: SNIPR Biome ApS. 2100 Copenhagen (DK)

(72) Inventors: SOMMER, Morten 2100 Copenhagen (DK) MARTINEZ, Virginia 2100 Copenhagen (DK) VAN DER HELM, Eric 2100 Copenhagen (DK) HAABER, Jakob Krause 2100 Copenhagen (DK) DE SANTIAGO TORIO, Ana 2100 Copenhagen (DK) GRØNDAHL, Christian 2100 Copenhagen (DK) CLUBE, Jasper 2100 Copenhagen (DK) (74) Representative: CMS Cameron McKenna Nabarro Olswang LLP  Cannon Place 78 Cannon Street London EC4N 6AF London EC4N 6AF (GB)