(19)

(11)

EP 3 784 265 A2

(12)

(88) Date of publication A3: 02.01.2020 (43) Date of publication: 03.03.2021 Bulletin 2021/09 (21) Application number: 19791705.7 (22) Date of filing: 17.04.2019

(51) International Patent Classification (IPC):  A61K 38/17(2006.01) A61P 3/10(2006.01) A61P 1/16(2006.01) C07K 14/47(2006.01) (86) International application number: PCT/IB2019/053194 (87) International publication number: WO 2019/207427 (31.10.2019 Gazette 2019/44)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 25.04.2018 US 201862662492 P (71) Applicant: Janssen Pharmaceutica NV 2340 Beerse (BE)	(72) Inventors: JIAN, Wenying Spring House, PA 19477 (US) PATCH, Raymond Spring House, PA 19477 (US) ZHANG, Rui Spring House, PA 19477 (US) ZHENG, Songmao Spring House, PA 19477 (US) HINKE, Simon Spring House, PA 19477 (US) (74) Representative: Warner, James Alexander  Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA London WC1B 5HA (GB)