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EP 3 784 661 A1

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(43) Date of publication: 03.03.2021 Bulletin 2021/09 (21) Application number: 19719799.9 (22) Date of filing: 18.04.2019

(51) International Patent Classification (IPC):  C07D 401/04(2006.01) C07D 471/04(2006.01) A61P 33/00(2006.01) A01P 17/00(2006.01) A61K 31/506(2006.01) A61K 31/437(2006.01) C07D 403/04(2006.01) C07D 417/04(2006.01) A01N 43/00(2006.01) A61K 31/4439(2006.01) A61K 31/4196(2006.01) (86) International application number: PCT/EP2019/060077 (87) International publication number: WO 2019/206799 (31.10.2019 Gazette 2019/44)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 25.04.2018 EP 18169333 09.08.2018 EP 18188221 21.11.2018 EP 18207519 (71) Applicant: Bayer Aktiengesellschaft 51373 Leverkusen (DE)

(72) Inventors: ARLT, Alexander 50859 Köln (DE) HALLENBACH, Werner 48531 Nordhorn (DE) SCHWARZ, Hans-Georg 46282 Dorsten (DE) FÜSSLEIN, Martin 40225 Düsseldorf (DE) WROBLOWSKY, Heinz-Juergen 40764 Langenfeld (DE) BUSCATO ARSEQUELL, Estella 60486 Frankfurt am Main (DE) LINKA, Marc 40223 Düsseldorf (DE) ILG, Kerstin 50670 Köln (DE) DAMIJONAITIS, Arunas Jonas 51371 Leverkusen (DE) EBBINGHAUS-KINTSCHER, Ulrich 44287 Dortmund (DE) GÖRGENS, Ulrich 40882 Ratingen (DE) CANCHO GRANDE, Yolanda 51373 Leverkusen (DE) JESCHKE, Peter 51467 Bergisch Gladbach (DE) TELSER, Joachim 42115 Wuppertal (DE) HEISLER, Iring 40593 Düsseldorf (DE) TURBERG, Andreas 42781 Haan (DE) (74) Representative: BIP Patents  c/o Bayer Intellectual Property GmbH Alfred-Nobel-Straße 10 40789 Monheim am Rhein 40789 Monheim am Rhein (DE)