(19)

(11)

EP 3 801 393 A1

(12)

(43) Date of publication: 14.04.2021 Bulletin 2021/15 (21) Application number: 19806625.0 (22) Date of filing: 24.05.2019

(51) International Patent Classification (IPC):  A61F 2/24(2006.01) (86) International application number: PCT/US2019/033942 (87) International publication number: WO 2019/227005 (28.11.2019 Gazette 2019/48)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 25.05.2018 US 201862676580 P (71) Applicant: Northwestern University Evanston, IL 60208 (US)	(72) Inventor: MCCARTHY, Patrick M. Chicago, Illinois 60611 (US) (74) Representative: KIPA AB  P O Box 1065 251 10 Helsingborg 251 10 Helsingborg (SE)