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EP 3 802 777 A1

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(43) Date of publication: 14.04.2021 Bulletin 2021/15 (21) Application number: 19811601.4 (22) Date of filing: 29.05.2019

(51) International Patent Classification (IPC):  C12M 1/32(2006.01) C12M 3/00(2006.01) B01L 3/00(2006.01) C12M 3/06(2006.01) C12M 1/00(2006.01) (86) International application number: PCT/US2019/034285 (87) International publication number: WO 2019/231977 (05.12.2019 Gazette 2019/49)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 29.05.2018 US 201862677468 P (71) Applicant: Vanderbilt University Nashville, TN 37240 (US)

(72) Inventors: WIKSWO, John, P. Brentwood, TN 37235 (US) SPIVEY, Eric, C. Nashville, TN 37209 (US) SCHAFFER, David, K. Nashville, TN 37206 (US) REISERER, Ronald, S. Nashville, TN 37217 (US) SEALE, Kevin, T. Nashville, TN 37215 (US) BLOCK, Frank, E. III Potomac, MD 20854 (US) (74) Representative: Dey, Michael  Weickmann & Weickmann Patent- und Rechtsanwälte PartmbB Postfach 860 820 81635 München 81635 München (DE)