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(11)

EP 3 807 246 A1

(12)

(43) Date of publication: 21.04.2021 Bulletin 2021/16 (21) Application number: 19819142.1 (22) Date of filing: 11.06.2019

(51) International Patent Classification (IPC):  C07D 207/34(2006.01) C07D 405/12(2006.01) C07D 413/12(2006.01) C07D 417/12(2006.01) C07D 513/04(2006.01) C07D 401/12(2006.01) C07D 405/14(2006.01) C07D 413/14(2006.01) C07D 451/06(2006.01) C07D 513/14(2006.01) (86) International application number: PCT/US2019/036611 (87) International publication number: WO 2019/241292 (19.12.2019 Gazette 2019/51)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 11.06.2018 US 201862683557 P 11.04.2019 US 201962832734 P (71) Applicant: Venatorx Pharmaceuticals, Inc. Malvern, PA 19355 (US)

(72) Inventors: BURNS, Christopher J. Malvern, Pennsylvania 19355 (US) COBURN, Glen Malvern, Pennsylvania 19355 (US) LIU, Bin Malvern, Pennsylvania 19355 (US) YAO, Jiangchao Malvern, Pennsylvania 19355 (US) BENETATOS, Christopher Malvern, Pennsylvania 19355 (US) BOYD, Steven A. Malvern, Pennsylvania 19355 (US) CONDON, Stephen M. Malvern, Pennsylvania 19355 (US) HAIMOWITZ, Thomas Malvern, Pennsylvania 19355 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)