(19)

(11)

EP 3 810 770 A1

(12)

(43) Date of publication: 28.04.2021 Bulletin 2021/17 (21) Application number: 19762195.6 (22) Date of filing: 20.08.2019

(51) International Patent Classification (IPC):  C12N 9/64(2006.01) C12N 15/864(2006.01) A61P 7/04(2006.01) A61K 38/48(2006.01) (86) International application number: PCT/GB2019/052339 (87) International publication number: WO 2020/039183 (27.02.2020 Gazette 2020/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 20.08.2018 US 201816105583 20.08.2018 GB 201813528 (71) Applicant: UCL BUSINESS LTD London W1T 4TP (GB)	(72) Inventors: NATHWANI, Amit London W1T 4TP (GB) MCINTOSH, Jenny London W1T 4TP (GB) (74) Representative: J A Kemp LLP  14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)