(19)
(11) EP 3 814 326 A1

(12)

(43) Date of publication:
05.05.2021 Bulletin 2021/18

(21) Application number: 19825897.2

(22) Date of filing: 25.06.2019
(51) International Patent Classification (IPC): 
C07D 239/22(2006.01)
C07D 403/04(2006.01)
C07D 417/10(2006.01)
A61K 31/506(2006.01)
 C07D 401/04(2006.01)
C07D 417/04(2006.01)
C07D 417/14(2006.01)
A61P 31/20(2006.01)
(86) International application number:
PCT/CN2019/092857
(87) International publication number:
WO 2020/001448 (02.01.2020 Gazette 2020/01)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 26.06.2018 WO PCT/CN2018/092875
09.08.2018 US 201862716823 P

(71) Applicant: Janssen Sciences Ireland Unlimited Company
Ringaskiddy, Co Cork (IE)

(72) Inventors:
  • DENG, Gang
    Shanghai 201201 (CN)
  • JIANG, Yimin
    Londonderry, New Hampshire 03053 (US)
  • LIU, Qian
    Shanghai 201210 (CN)
  • LIANG, Chao
    Shanghai 201210 (CN)
  • WAN, Zhao-Kui
    Shanghai 201210 (CN)
  • CHEUNG, Wing Shun
    Shanghai 201210 (CN)
  • CHENG, Zhanling
    Shanghai 200129 (CN)
  • XU, Yanping
    Noblesville, Indiana 46062 (US)

(74) Representative: Garcia Prieto, Maria 
Johnson & Johnson Patent Law Department Turnhoutseweg 30
2340 Beerse
2340 Beerse (BE)

   


(54) DIHYDROPYRIMIDINE DERIVATIVES AND USES THEREOF IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES