(19)
(11) EP 3 823 979 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
26.02.2025 Bulletin 2025/09

(45) Mention of the grant of the patent:
18.12.2024 Bulletin 2024/51

(21) Application number: 19742045.8

(22) Date of filing: 19.07.2019
(51) International Patent Classification (IPC): 
C07K 14/03(2006.01)
(52) Cooperative Patent Classification (CPC):
G01N 2333/03; C07K 14/005; C07K 2319/00; C12N 2710/16122
(86) International application number:
PCT/EP2019/069562
(87) International publication number:
WO 2020/016433 (23.01.2020 Gazette 2020/04)

(54)

METHODS FOR SCREENING AND IDENTIFYING AGENTS THAT INHIBIT OR MODULATE THE NUCLEAR EGRESS COMPLEX OF HERPESVIRUSES

VERFAHREN ZUM SCREENING UND ZUR IDENTIFIZIERUNG VON WIRKSTOFFEN, DIE DEN NUKLEAREN AUSTRITTSKOMPLEX VON HERPESVIREN HEMMEN ODER MODULIEREN

PROCÉDÉS DE CRIBLAGE ET D'IDENTIFICATION D'AGENTS QUI INHIBENT OU MODULENT LE COMPLEXE DE SORTIE NUCLÉAIRE DES VIRUS DE L'HERPÈS

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 20.07.2018 EP 18184806

(43) Date of publication of application:
26.05.2021 Bulletin 2021/21

(73) Proprietors:
  • AiCuris Anti-infective Cures AG
    42117 Wuppertal (DE)
  • Friedrich-Alexander-Universität Erlangen-Nürnberg
    91054 Erlangen (DE)

(72) Inventors:
  • MARSCHALL, Manfred
    90408 Nürnberg (DE)
  • MULLER, Yves
    91054 Erlangen (DE)
  • STICHT, Heinrich
    90762 Fürth (DE)
  • EICHLER, Jutta
    91058 Erlangen (DE)

(74) Representative: Kilger, Ute 
Boehmert & Boehmert Anwaltspartnerschaft mbB Pettenkoferstrasse 22
80336 München
80336 München (DE)


(56) References cited: : 
WO-A1-01/64942
WO-A2-2011/138040
 WO-A1-2014/089158
   
  • KENDRA E. LEIGH ET AL: "Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 112, no. 29, 6 July 2015 (2015-07-06), US, pages 9010 - 9015, XP055231618, ISSN: 0027-8424, DOI: 10.1073/pnas.1511140112
  • JANNA M. BIGALKE ET AL: "The Great (Nuclear) Escape: New Insights into the Role of the Nuclear Egress Complex of Herpesviruses", JOURNAL OF VIROLOGY., vol. 89, no. 18, 24 June 2015 (2015-06-24), US, pages 9150 - 9153, XP055522872, ISSN: 0022-538X, DOI: 10.1128/JVI.02530-14
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).