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(11)

EP 3 826 667 A2

(12)

(88) Date of publication A3: 16.05.2019 (43) Date of publication: 02.06.2021 Bulletin 2021/22 (21) Application number: 18857242.4 (22) Date of filing: 18.09.2018

(51) International Patent Classification (IPC):  A61K 39/00(2006.01) A61K 51/00(2006.01) A61P 35/04(2006.01) A61K 39/395(2006.01) A61P 35/00(2006.01) A61P 43/00(2006.01) (86) International application number: PCT/US2018/051610 (87) International publication number: WO 2019/056023 (21.03.2019 Gazette 2019/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 18.09.2017 US 201762560143 P (71) Applicant: The Regents of the University of California Oakland, CA 94607-5200 (US)	(72) Inventors: CONKLIN, Dylan Woodland Hills CA 91364 (US) SLAMON, Dennis Woodland Hills CA 91367 (US) O'BRIEN, Neil Santa Monica CA 90405 (US) PALAZZOLO, Mike Thousand Oaks CA 91362 (US) VON EUW, Erika Los Angeles CA 90066 (US) (74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB  Siebertstrasse 3 81675 München 81675 München (DE)