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EP 3 830 093 A1

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(43) Date of publication: 09.06.2021 Bulletin 2021/23 (21) Application number: 19750013.5 (22) Date of filing: 25.07.2019

(51) International Patent Classification (IPC):  C07D 495/04(2006.01) C07D 401/14(2006.01) A61K 31/444(2006.01) A61P 35/00(2006.01) C07D 417/14(2006.01) C07D 403/14(2006.01) A61K 31/55(2006.01) (86) International application number: PCT/US2019/043500 (87) International publication number: WO 2020/023782 (30.01.2020 Gazette 2020/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 27.07.2018 US 201862711164 P (71) Applicant: Biotheryx, Inc. Chappaqua, NY 10514 (US)

(72) Inventors: CHAN, Kyle W.H. Chappaqua, New York 10514 (US) CHOURASIA, Aparajita Hoskote Chappaqua, New York 10514 (US) ERDMAN, Paul E. Chappaqua, New York 10514 (US) FUNG, Leah Chappaqua, New York 10514 (US) HECHT, David Aaron Chula Vista, California 91913 (US) MERCURIO, Frank Chappaqua, New York 10514 (US) SULLIVAN, Robert Chappaqua, New York 10514 (US) VACCA, Joseph P. Telford, Pennsylvania 18969 (US) (74) Representative: Viering, Jentschura & Partner mbB Patent- und Rechtsanwälte  Hamborner Straße 53 40472 Düsseldorf 40472 Düsseldorf (DE)