(19)

(11)

EP 3 830 253 A1

(12)

(43) Date of publication: 09.06.2021 Bulletin 2021/23 (21) Application number: 19756111.1 (22) Date of filing: 30.07.2019

(51) International Patent Classification (IPC):  C12N 9/10(2006.01) C12P 7/26(2006.01) C12P 13/00(2006.01) (86) International application number: PCT/EP2019/070561 (87) International publication number: WO 2020/025646 (06.02.2020 Gazette 2020/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 30.07.2018 EP 18186426 (71) Applicant: University College Cork-National University of Ireland Cork Cork (IE)	(72) Inventors: MAGUIRE, Anita Cork (IE) GAVIN, Declan Cork (IE) O'GARA, Fergal Cork (IE) REEN, Jerry Cork (IE) (74) Representative: Purdylucey Intellectual Property  6-7 Harcourt Terrace D02 FH73 Dublin 2 D02 FH73 Dublin 2 (IE)