(19)

(11)

EP 3 843 708 A2

(12)

(88) Date of publication A3: 14.05.2020 (43) Date of publication: 07.07.2021 Bulletin 2021/27 (21) Application number: 19868839.2 (22) Date of filing: 30.09.2019

(51) International Patent Classification (IPC):  A61K 9/50(2006.01) B82Y 5/00(2011.01) A61K 47/42(2017.01) (86) International application number: PCT/TR2019/050810 (87) International publication number: WO 2020/072019 (09.04.2020 Gazette 2020/15)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.10.2018 TR 201814254 (71) Applicant: Ege Universitesi 35100 Izmir (TR)	(72) Inventors: BAYRAKTAR, Oguz Bayrakl / zmir (TR) YAHSI, Yasemin 35040 Bornova/ zmir (TR) KÖSE, Merve Deniz 35040 Bornova/ zmir (TR) (74) Representative: Kayahan, Senem  Yalciner Patent and Consulting Ltd. Tunus Cad. No: 85/3-4 Kavaklidere Cankaya 06680 Ankara 06680 Ankara (TR)