(19)

(11)

EP 3 846 798 A1

(12)

(43) Date of publication: 14.07.2021 Bulletin 2021/28 (21) Application number: 18778780.9 (22) Date of filing: 07.09.2018

(51) International Patent Classification (IPC):  A61K 31/365(2006.01) A61P 37/06(2006.01) A61K 31/5377(2006.01) A61P 37/00(2006.01) (86) International application number: PCT/US2018/050079 (87) International publication number: WO 2020/050863 (12.03.2020 Gazette 2020/11)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicant: Okava Pharmaceuticals, Inc. San Francisco, California 94109 (US)	(72) Inventors: KLOTSMAN, Michael San Francisco, California 94109 (US) SHIVANAND, Padmaja Seattle, Washington 98136 (US) ANDERSON, Wayne, H. Raleigh, North Carolina 27613 (US) SATHYAN, Gayatri Bangalore, Karnataka 560103 (IN) (74) Representative: Eisenführ Speiser  Patentanwälte Rechtsanwälte PartGmbB Postfach 31 02 60 80102 München 80102 München (DE)