(19)

(11)

EP 3 850 478 A1

(12)

(43) Date of publication: 21.07.2021 Bulletin 2021/29 (21) Application number: 19858809.7 (22) Date of filing: 12.09.2019

(51) International Patent Classification (IPC):  G06F 8/41(2018.01) G06F 9/50(2006.01) (86) International application number: PCT/US2019/050870 (87) International publication number: WO 2020/056176 (19.03.2020 Gazette 2020/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 13.09.2018 US 201862730813 P 30.11.2018 US 201862773581 P (71) Applicant: The University of Chicago Chicago, IL 60615 (US)	(72) Inventors: CHONG, Frederic T. Chicago, Illinois 60615 (US) SHI, Yunong Chicago, Illinois 60615 (US) LEUNG, Nelson Chicago, Illinois 60615 (US) GOKHALE, Pranav Chicago, Illinois 60615 (US) HOFFMANN, Henry Chicago, Illinois 60615 (US) SCHUSTER, David Chicago, Illinois 60615 (US) (74) Representative: Dehns  St. Bride's House 10 Salisbury Square London EC4Y 8JD London EC4Y 8JD (GB)