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(11)

EP 3 853 346 A1

(12)

(43) Date of publication: 28.07.2021 Bulletin 2021/30 (21) Application number: 19861733.4 (22) Date of filing: 20.09.2019

(51) International Patent Classification (IPC):  C12N 5/07(2010.01) C12N 5/0797(2010.01) C12N 5/0789(2010.01) (86) International application number: PCT/US2019/052231 (87) International publication number: WO 2020/061500 (26.03.2020 Gazette 2020/13)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 21.09.2018 US 201862734314 P (71) Applicant: Worcester Polytechnic Institute Worcester, MA 01609 (US)	(72) Inventors: GAUDETTE, Glenn Worcester, Massachusetts 01609 (US) DOMINKO, Tanja Worcester, Massachusetts 01609 (US) GERSHLAK, Joshua Worcester, Massachusetts 01609 (US) PERLMAN, Brent Worcester, Massachusetts 01609 (US) (74) Representative: Ricker, Mathias  Wallinger Ricker Schlotter Tostmann Patent- und Rechtsanwälte Partnerschaft mbB Zweibrückenstrasse 5-7 80331 München 80331 München (DE)