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EP 3 860 567 A1

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(43) Date of publication: 11.08.2021 Bulletin 2021/32 (21) Application number: 19869416.8 (22) Date of filing: 27.09.2019

(51) International Patent Classification (IPC):  A61K 9/00(2006.01) A61K 9/16(2006.01) A61K 39/00(2006.01) A61K 47/00(2006.01) A61K 9/08(2006.01) A61K 9/19(2006.01) A61K 39/395(2006.01) (86) International application number: PCT/US2019/053462 (87) International publication number: WO 2020/072306 (09.04.2020 Gazette 2020/15)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.10.2018 US 201862739542 P (71) Applicant: Amgen Inc. Thousand Oaks, California 91320 (US)	(72) Inventors: JAGANNATHAN, Bharadwaj Thousand Oaks, California 91320-1799 (US) HUH, Joon Thousand Oaks, California 91320-1799 (US) TREUHEIT, Michael Thousand Oaks, California 91320-1799 (US) SHAN, Daxian Thousand Oaks, California 91320-1799 (US) (74) Representative: J A Kemp LLP  14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)