(19)
(11) EP 3 861 012 A1

(12)

(43) Date of publication:
11.08.2021 Bulletin 2021/32

(21) Application number: 19868458.1

(22) Date of filing: 04.10.2019
(51) International Patent Classification (IPC): 
C07K 14/195(2006.01)
C12N 15/11(2006.01)
 C12N 15/01(2006.01)
(86) International application number:
PCT/US2019/054869
(87) International publication number:
WO 2020/073005 (09.04.2020 Gazette 2020/15)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 04.10.2018 US 201862741470 P
04.10.2018 US 201862741475 P

(71) Applicant: The Regents of the University of Colorado, a body corporate
Denver, CO 80203 (US)

(72) Inventors:
  • GILL, Ryan T.
    Boulder, Colorado 80303 (US)
  • LIU, Rongming
    Boulder, Colorado 80303 (US)

(74) Representative: Mewburn Ellis LLP 
Aurora Building Counterslip
Bristol BS1 6BX
Bristol BS1 6BX (GB)

   


(54) ENGINEERED CHIMERIC NUCLEIC ACID GUIDED NUCLEASES, COMPOSITIONS, METHODS FOR MAKING, AND SYSTEMS FOR GENE EDITING