(19)

(11)

EP 3 876 945 A1

(12)

(43) Date of publication: 15.09.2021 Bulletin 2021/37 (21) Application number: 19881364.4 (22) Date of filing: 16.10.2019

(51) International Patent Classification (IPC):  A61K 31/575(2006.01) A61P 1/16(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/575; A61P 1/16 (86) International application number: PCT/IL2019/051121 (87) International publication number: WO 2020/095293 (14.05.2020 Gazette 2020/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 07.11.2018 US 201816182767 (71) Applicant: Galmed Research and Development Ltd. 6578317 Tel Aviv (IL)	(72) Inventors: HAYARDENY-NISSIMOV, Liat 6939104 Tel Aviv (IL) GORFINE, Tali 6494210 Tel Aviv (IL) BAHARAFF, Allen 6215441 Tel Aviv (IL) MATO DE LA PAZ, Jose M. 48992 Getxo (ES) (74) Representative: Pearl Cohen Zedek Latzer Baratz UK LLP  The Gridiron Building One Pancras Square London N1C 4AG London N1C 4AG (GB)