NAPHTHYRIDINONE-ANILINE COMPOUNDS FOR TREATMENT OF DERMAL DISORDERS

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EP 3 883 567 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	02.07.2025 Bulletin 2025/27

(45)	Mention of the grant of the patent:
	28.05.2025 Bulletin 2025/22

(21)	Application number: 19886663.4

(22)	Date of filing: 20.11.2019

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International Patent Classification (IPC):

C07D 471/04^(2006.01)
A61P 9/06^(2006.01)

A61K 31/4375^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	C07D 471/04; A61P 9/06

(86)	International application number:
	PCT/US2019/000070

(87)	International publication number:
	WO 2020/106308 (28.05.2020 Gazette 2020/22)

(54)	NAPHTHYRIDINONE-ANILINE COMPOUNDS FOR TREATMENT OF DERMAL DISORDERS NAPHTHYRIDINON-ANILIN-VERBINDUNGEN ZUR BEHANDLUNG VON HAUTERKRANKUNGEN COMPOSÉS NAPHTHYRIDINONE-ANILINE DESTINÉS AU TRAITEMENT D'AFFECTIONS DE LA PEAU

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME
	Designated Validation States:
	KH MA MD TN

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Priority:

20.11.2018 US 201862769866 P

(43)	Date of publication of application:
	29.09.2021 Bulletin 2021/39

(73)	Proprietor: NFlection Therapeutics, Inc.
	Boston, Massachusetts 02116 (US)

(72)	Inventors:
	KINCAID, John Boston, Massachusetts 02116 (US) DUNCTON, Matthew Boston, Massachusetts 02116 (US)

(74)	Representative: J A Kemp LLP
	80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)

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References cited: :

WO-A1-2005/121142
US-A- 5 854 257
US-A1- 2006 276 646

US-A- 4 271 164
US-A- 6 150 359

LU HEJUN ET AL: "Structure-based design and synthesis of bicyclic fused-pyridines as MEK inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 24, no. 11, 3 April 2014 (2014-04-03), pages 2555 - 2559, XP028660031, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2014.03.086

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).