(19)

(11)

EP 3 883 607 A2

(12)

(88) Date of publication A3: 02.07.2020 (43) Date of publication: 29.09.2021 Bulletin 2021/39 (21) Application number: 19887792.0 (22) Date of filing: 19.11.2019

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61K 9/08(2006.01) C07K 16/24(2006.01) (52) Cooperative Patent Classification (CPC): A61K 2039/505; C07K 16/244; A61K 45/06; A61K 2039/545; C07K 2317/76; C07K 2317/21; A61P 17/06 (86) International application number: PCT/IB2019/059939 (87) International publication number: WO 2020/104943 (28.05.2020 Gazette 2020/22)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 20.11.2018 US 201862769889 P 25.01.2019 US 201962796673 P 26.02.2019 US 201962810617 P 13.03.2019 US 201962817711 P 15.10.2019 US 201962915115 P (71) Applicant: Janssen Biotech, Inc. Horsham, PA 19044 (US)

(72) Inventors: ANGSANA, Julianty San Diego, CA 92121 (US) BRANIGAN, Patrick Spring House, PA 19477 (US) DEPRIMO, Samuel San Diego, CA 92121 (US) FLAVIN, Susan Spring House, PA 19477 (US) LI, Shu Spring House, PA 19477 (US) LIU, Xuejun San Diego, CA 92130 (US) MUNOZ, Ernesto San Diego, CA 92121 (US) RANDAZZO, Bruce Rydal, PA 19046 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)