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EP 3 891 224 A1

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(43) Date of publication: 13.10.2021 Bulletin 2021/41 (21) Application number: 19892945.7 (22) Date of filing: 05.12.2019

(51) International Patent Classification (IPC):  C09B 23/10(2006.01) C09B 23/01(2006.01) C07D 519/00(2006.01) A61K 31/437(2006.01) C07D 407/08(2006.01) C07D 405/14(2006.01) A61K 31/352(2006.01) (52) Cooperative Patent Classification (CPC): C07D 311/60; C07D 311/92; C07D 403/08; C07D 405/08; C07D 405/14; C07D 409/08; C07D 491/22; C09B 23/0016; C09B 23/0066; C09B 23/04; C09B 23/06; C09B 23/086 (86) International application number: PCT/US2019/064790 (87) International publication number: WO 2020/118116 (11.06.2020 Gazette 2020/24)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 05.12.2018 US 201862775788 P (71) Applicant: The Regents of the University of California Oakland, CA 94607 (US)	(72) Inventors: SLETTEN, Ellen, M. Los Angeles, CA 90095-7191 (US) COSCO, Emily, D. Los Angeles, CA 90095-7191 (US) SPEARMAN, Anthony Los Angeles, CA 90095-7191 (US) PENGSHUNG, Monica Los Angeles, CA 90095-7191 (US) (74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB  Siebertstraße 3 81675 München 81675 München (DE)