(19)

(11)

EP 3 891 507 A1

(12)

(43) Date of publication: 13.10.2021 Bulletin 2021/41 (21) Application number: 19813045.2 (22) Date of filing: 06.12.2019

(51) International Patent Classification (IPC):  G01N 33/68(2006.01) G01N 33/50(2006.01) (52) Cooperative Patent Classification (CPC): G01N 33/5091; G01N 2333/912; G01N 33/689; G01N 2800/367 (86) International application number: PCT/EP2019/084015 (87) International publication number: WO 2020/115291 (11.06.2020 Gazette 2020/24)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 06.12.2018 EP 18210761 (71) Applicant: Universität zu Köln 50923 Köln (DE)	(72) Inventors: VON BRANDENSTEIN, Melanie 51789 Lindlar (DE) KÖDITZ, Barbara 52353 Düren (DE) FRIES, Jochen 50259 Pulheim (DE) FUNKE, Timo 50674 Köln (DE) SALEM, Johannes 50939 Köln (DE) (74) Representative: Lahrtz, Fritz  Patentanwälte Isenbruck Bösl Hörschler PartG mbB Seckenheimer Landstr. 4 68163 Mannheim Seckenheimer Landstr. 4 68163 Mannheim (DE)