(19)
(11) EP 3 927 824 A2

(12)

(88) Date of publication A3:
29.07.2021

(43) Date of publication:
29.12.2021 Bulletin 2021/52

(21) Application number: 20842799.7

(22) Date of filing: 18.12.2020
(51) International Patent Classification (IPC): 
C12N 15/10(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 15/1093
(86) International application number:
PCT/US2020/066013
(87) International publication number:
WO 2021/127436 (24.06.2021 Gazette 2021/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 19.12.2019 US 201962950670 P

(71) Applicants:
  • Illumina, Inc.
    San Diego, CA 92122 (US)
  • University of Washington
    Seattle, Washington 98105-4721 (US)

(72) Inventors:
  • SHENDURE, Jay
    Seattle, Washington 98105 (US)
  • CUSANOVICH, Darren
    Seattle, Washington 98105 (US)
  • DAZA, Riza
    Seattle, Washington 98105 (US)
  • STEEMERS, Frank
    San Diego, California 92122 (US)

(74) Representative: Dehns 
St. Bride's House 10 Salisbury Square
London EC4Y 8JD
London EC4Y 8JD (GB)

   


(54) HIGH-THROUGHPUT SINGLE-CELL LIBRARIES AND METHODS OF MAKING AND OF USING